Which teeth are good candidates?
All teeth contain dental pulp, and therefore are all a potential source of stem cells. However, research has shown that in deciduous teeth, the four lower incisors (laterals and central) are the best sources of stem cells. In the course of treatment under the dentist’s supervision, any teeth in which the pulp chamber is exposed or teeth which are extracted would be acceptable, as long as there is healthy pulp present.
What about permanent teeth?
For permanent teeth, the research has indicated that the third molars are the best source of stem cells, due to the fact that these teeth emerge at a later time. Impacted molars which necessitate extraction or removal of wisdom teeth due to crowding or to facilitate orthodontic treatment would be acceptable. Endodontic therapy whereby the vital, non-hyperemic pulp is exposed would also be acceptable. Based on the dental practitioner’s’ judgment, periodontal treatment does not necessarily eliminate teeth as a source of stem cells. Generally all teeth which contain healthy pulp are acceptable.
A suitable evaluation of each client’s oral health is essential. The oral examination conducted by the dental practitioner will provide insight to the general health conditions of the client storing or donating their teeth or dental pulp, with emphasis on mucosal pathologies, clinical signs of periodontal inflammation, and pathologic swellings in the tooth area (suggesting abscesses or bacterial infection). Poor oral hygiene or periodontal lesions should be avoided, as such conditions could negatively affect the future uses of the stem cells. If the donor is in good general health (disease free), no pre-treatment (dental hygiene) is required.
Teeth will not be accepted if:
- Severe caries are present in tooth
- Significant enamel demineralization is present
- Gross plaque
- Significant gingivitis
What preparations are needed?
Prior to extraction, it is strongly recommended that the crown(s) of each candidate tooth (teeth) be cleaned with an appropriate disinfectant rinse to decontaminate the candidate tooth (teeth) and to avoid any postoperative infections.
Do I need to handle any paperwork?
Nope! We’ll take care of all enrollment paperwork directly with your patient, once you refer them to us.
Why should I choose to partner with NDPL?
The NDPL laboratory and storage facility is one of the longest running cryogenic laboratories in the world. Our affiliate, New England Cryogenic, has been serving both domestic and international clients since 1971. In addition to the processing and banking of dental pulp stem cells, our laboratory also banks unfertilized eggs, sperm, cord blood, and other human tissue. Managed by highly trained biologists and technicians, our FDA registered lab offers you the combination of experience, cutting-edge facilities, and integrity. Rest assured knowing you’re doing the best for your clients by partnering with NDPL.
NDPL will defray the cost of administration and any additional procedures involved in assisting your patients as they save their stem cells. NDPL is offering dentists a reimbursement of $200 per enrolled patient, for any NDPL stem cell preservation program.
What if a patient wants to donate teeth?
Besides serving as a family dental stem cell bank, NDPL is also a research facility, and we are actively looking for donated teeth. Please have your patient request a donor release form and collection kit from NDPL prior to the date of extraction.
Can my client enroll on the extraction date?
Yes! Instruct your patient to enroll with us online, and we will overnight their collection kit to your office. Place the tooth/teeth in the same solution you would use for avulsed teeth, and store at room temperature until the kit arrives the next day. Transfer the teeth into the collection kit vial, and the kit will be ready for pickup!